Table 1.
Naïve Ctrl | Spastic Pre | Spastic Tiz (#) | Spastic Iso (##) | |
---|---|---|---|---|
M max (mV) | 8.61 ± 0.36 | 11.22 ± 1.10 | 9.39 ± 0.85 | 9.68 ± 1.03 |
H max (mV) | 2.06 ± 0.26 | 3.94 ± 0.22 | 2.15 ± 0.33 | 1.95 ± 0.32 |
H / M ratio | 0.24 ± 0.03 | 0.35 ± 0.05* | 0.23 ± 0.03** | 0.20 ± 0.04*** |
Tizanidine was administered i.p. (1 mg kg -1)
Animals were anesthetized with 2% Isoflurane
p<0.05 vs. Naïve Control rats
p<0.05 vs. spastic non-treated animals
p<0.05 vs. spastic non-treated animals
(t-test with Bonferroni correction)