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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Biol Psychiatry. 2011 Jul 14;70(9):866–872. doi: 10.1016/j.biopsych.2011.05.030

Figure 1.

Figure 1

Methodology for spectroscopy. (a, b) the MRS voxel (yellow, 3 cm × 3cm × 3cm voxel) was placed over the anatomical location of the dlPFC. Edited MR spectra (c) allow the quantification of GABA concentration by extracting the area under the GABA peak (39-41, 68). In a similar way, we extracted a measure of glutamate+glutamine, Glx, (also marked is the N-acetyl-aspartate peak, NAA). The GABA peak will contain signal from co-edited macromolecules, but although we do not know the exact contribution, we do not expect any individual differences in macromolecules to drive any correlation with our behavioural measures.