Table 2.
Demographic characteristics and clinical features of survivors of intensive care for three datasets. Figure are number (percentage) of patients, median (range), or mean (SD)
| A—Guy's development set
|
B—Guy's validation set
|
C—RIP users group*
|
P value for A v B
|
P value for A v C
|
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ward deaths (n=200) | Hospital survivors (n=5275) | P value | Ward deaths (n=49) | Hospital survivors (n=1087) | P value | Ward deaths (n=909) | Hospital survivors (n=6404) | P value | Ward deaths | Hospital survivors | Ward deaths | Hospital survivors | |||||
| Median age (years) | 67 (31-93) | 62 (17-101) | 0.0001 | 70 (27-84) | 62 (16-90) | 0.0001 | 72 (16-96) | 63 (16-96) | 0.0001 | 0.089 | 0.579 | 0.0001 | 0.251 | ||||
| Men | 130 (65) | 3676 (70) | 0.158 | 32 (65) | 727 (67) | 0.819 | 507 (56) | 3882 (61) | 0.005 | 0.968 | 0.068 | 0.017 | 0.0001 | ||||
| Patients with chronic ill health | 79 (40) | 1173 (22) | 0.0001 | 22 (45) | 235 (22) | 0.0001 | 244 (27) | 893 (14) | 0.0001 | 0.490 | 0.655 | 0.0001 | 0.0001 | ||||
| Mean day 1 APACHE II score | 19.1 (6.9) | 13.5 (5.3) | 0.0001 | 20.2 (6.1) | 14.8 (6.0) | 0.0001 | 17.3 (6.7) | 11.5 (5.9) | 0.0001 | 0.244 | 0.0001 | 0.0001 | 0.0001 | ||||
| Mean last APACHE II score | 15.8 (6.1) | 11.9 (4.5) | 0.0001 | 16.9 (5.1) | 12.2 (22.2) | 0.0001 | 15.7 (6.6) | 9.8 (5.2) | 0.0001 | 0.145 | 0.066 | 0.759 | 0.0001 | ||||
| Mean day 1 risk of death | 30.4 (22.6) | 11.2 (12.8) | 0.0001 | 37.3 (21.0) | 17.6 (17.3) | 0.0001 | 29.3 (20.7) | 13.7 (14.2) | 0.0001 | 0.030 | 0.0001 | 0.855 | 0.0001 | ||||
| Mean day 1 APP | 13.4 (6.1) | 9.6 (4.6) | 0.0001 | 13.7 (5.5) | 10.7 (5.2) | 0.0001 | 11.5 (6.5) | 7.7 (5.2) | 0.0001 | 0.559 | 0.0001 | 0.0001 | 0.0001 | ||||
| Mean last APP | 10.1 (5.5) | 8.0 (3.7) | 0.0001 | 10.5 (4.6) | 8.1(3.8) | 0.0001 | 9.9 (6.4) | 5.9 (4.4) | 0.0001 | 0.514 | 0.385 | 0.285 | 0.0001 | ||||
| Mean day 1 OFS | 19.6 (7.3) | 13.7 (5.5) | 0.0001 | 20.0 (7.4) | 14.0 (7.0) | 0.0001 | 17.8 (7.1) | 11.7 (6.2) | 0.0001 | 0.415 | 0.032 | 0.001 | 0.0001 | ||||
| Mean last OFS | 16.1 (6.4) | 12.0 (4.6) | 0.0001 | 17.3 (5.3) | 11.9 (5.3) | 0.0001 | 16.1 (7.0) | 9.9 (5.4) | 0.0001 | 0.139 | 0.944 | 0.869 | 0.0001 | ||||
| Patients with ⩾1 organs in failure at ICU discharge | 88 (44) | 1252 (24) | 0.0001 | 26 (53) | 333 (31) | 0.01 | 495 (54) | 2319 (36) | 0.0001 | 0.558 | 0.0001 | 0.003 | 0.0001 | ||||
| Median day 1 TISS points | 34 (4-78) | 33 (3-89) | 0.187 | 37 (2-93) | 43 (20-74) | 0.0001 | 33 (2-79) | 28 (2-93) | 0.0001 | 0.0001 | 0.0001 | 0.216 | 0.0001 | ||||
| Median last TISS points | 28 (4-54) | 31 (2-79) | 0.0001 | 33 (20-65) | 34 (2-75) | 0.502 | 28 (1-75) | 23 (1-79) | 0.0001 | 0.0001 | 0.0001 | 0.155 | 0.0001 | ||||
| Cadiothoracic patients | 30 (15) | 3103 (59) | 0.0001 | 1 (2) | 343 (32) | 0.0001 | 7 (1) | 193 (3) | 0.0001 | 0.014 | 0.0001 | 0.0001 | 0.0001 | ||||
| Ventilated patients | 136 (68) | 4244 (81) | 0.0001 | 45 (92) | 960 (88) | 0.450 | 498 (55) | 2658 (42) | 0.0001 | 0.001 | 0.0001 | 0.0001 | 0.0001 | ||||
| Median ventilated days | 3 (0-52) | 1 (1-260) | 0.0001 | 7 (1-87) | 1 (1-73) | 0.0001 | 3 (1-53) | 2 (1-198) | 0.0001 | 0.0001 | 0.0001 | 0.096 | 0.0001 | ||||
| Dialysed patients | 42 (21) | 247 (5) | 0.0001 | 23 (47) | 138 (13) | 0.0001 | 31 (3) | 116 (2) | 0.001 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | ||||
| Median dialysis days | 4 (1-34) | 4 (1-57) | 0.355 | 9 (1-45) | 4 (1-57) | 0.059 | 4 (1-28) | 4 (1-75) | 0.785 | 0.233 | 0.143 | 0.424 | 0.976 | ||||
| Median length of ICU stay | 3 (1-64) | 1 (1-283) | 0.0001 | 8 (2-112) | 3 (2-79) | 0.0001 | 3 (1-54) | 2 (1-219) | 0.0001 | 0.0001 | 0.0001 | 0.205 | 0.0001 | ||||
| Median length of hospital stay | 10 (0-303) | 7 (0-677) | 0.0001 | 10 (1-127) | 6 (0-281) | 0.049 | 6 (0-256) | 9 (0-270) | 0.0001 | 0.849 | 0.0001 | 0.0001 | 0.0001 | ||||
APP=acute physiology points, OFS=organ failure score, TISS=therapeutic intervention score, RIP=Riyadh ICU program.