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. 2011 Oct 12;6(10):e25636. doi: 10.1371/journal.pone.0025636

Figure 4. Effects of c-SRC kinase activity on barium-mediated anchorage-independent growth and invasion of HaCaT cells.

Figure 4

A and B, Number of colonies by the colony formation assay (A) and number of invading cells by the invasion assay (B) are presented in a graph (left) and photographs (right). C, Phosphorylated levels of c-SRC (P-SRC) and protein expression levels of c-SRC (C) in HaCaT cells are presented. Cells treated with 5 µM of barium (lane 2), 1 µM of the SRC inhibitor PP2 (lane 3), 5 µM of barium and 1 µM of PP2 (lane 4) and nil control (lane 1) for 24 hours are presented. * Significantly different (*, p<0.05) from the control by the Kruskal-Wallis test.