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. 2011 Oct 12;6(10):e26096. doi: 10.1371/journal.pone.0026096

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Zembe et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Comparison of entropy scores between peptides recognized exclusively by clade C peptide reagents (red) and those mutually recognized in all the four clades tested (purple). (B) Frequency of responders to epitopes recognized by clade C reagents (red) compared to those mutually recognized in all four clades (purple). (C) Comparison of entropy score of peptides with different levels of cross-reactivities. Peptides were categorized into those recognized in one (red), two (purple) or three or more (green) variants of the peptide sets. The non-parametric one way ANOVA and Kruskal-Wallis test was used to test for differences in the median entropy scores among the different recognition categories.