Table 2. Effects of PTH versus bisphosphonates on volumetric BMD of the spine.
Author (Ref.) | Volumetric BMD of the spine | Weight (%) | Weighted mean difference (WMD) of BMD (95%CI) | |||
PTH | bisphosphonates | |||||
n | percent change(%) | n | percent change(%) | |||
Finkelstein 2003 [23] | 20 | 48.0±27.9 | 28 | 3.0±7.8 | 24.19 | 45.00 [32.44, 57.56] |
Black 2003 [10] | 119 | 25.3±15.1 | 60 | 10.3±8.1 | 26.78 | 15.00 [11.60, 18.40] |
McClung 2005 [22] | 26 | 19.0±17.3 | 23 | 3.8±16.3 | 25.35 | 15.20 [5.79, 24.61] |
Finkelstein 2010 [20] | 20 | 61.0±31.0 | 29 | 1.0±7.0 | 23.68 | 60.00 [46.18, 73.82] |
Pooled | 185 | 140 | 100 | 32.96 [13.81, 52.12] | ||
Heterogeneity | Tau2 = 353.63; Chi2 = 56.19, df = 3; I2 = 95% p<0.01 |