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. 2011 Oct 12;6(10):e26267. doi: 10.1371/journal.pone.0026267

Table 2. Effects of PTH versus bisphosphonates on volumetric BMD of the spine.

Author (Ref.) Volumetric BMD of the spine Weight (%) Weighted mean difference (WMD) of BMD (95%CI)
PTH bisphosphonates
n percent change(%) n percent change(%)
Finkelstein 2003 [23] 20 48.0±27.9 28 3.0±7.8 24.19 45.00 [32.44, 57.56]
Black 2003 [10] 119 25.3±15.1 60 10.3±8.1 26.78 15.00 [11.60, 18.40]
McClung 2005 [22] 26 19.0±17.3 23 3.8±16.3 25.35 15.20 [5.79, 24.61]
Finkelstein 2010 [20] 20 61.0±31.0 29 1.0±7.0 23.68 60.00 [46.18, 73.82]
Pooled 185 140 100 32.96 [13.81, 52.12]
Heterogeneity Tau2  = 353.63; Chi2  = 56.19, df  = 3; I2  = 95% p<0.01