Figure 5. Hepatocellular neoplasms in Tg05 wildtype HBV transgenic mice.
(A) In situ view of a Tg05 liver with tumor nodules (arrows). (B) Hematoxylin and eosin stained section of a normal liver in 24-month old Tg05 mouse, showing the lack of inflammation. (C) Hematoxylin and eosin stained section of a liver tumor, showing a hepatocellular adenoma (arrows) with mild atypia and compression of surrounding liver parenchyma. (D) Hematoxylin and eosin stained section of a liver tumor, showing a HCC with trabecular pattern.