FIG. 3.

(A) Three-dimensional Lattice–Boltzmann simulation of local shear stresses resulting from fluid flow through a porous polycaprolactone scaffold (white) seeded with marrow-derived progenitor cells in a perfusion bioreactor. (B) Micro-CT images of mineralized matrix synthesis in perfused constructs compared with constructs cultured under static conditions. (C) 9 mm long mineralized construct produced under dynamic culture using stem cells seeded on a polycaprolactone scaffold. Color images available online at www.liebertonline.com/ten.