Table 4.

Overall survival, intention-to-treat and progression-free survival Probabilities

t-year	Overall Cohort	Non-FISH	FISH	Std Risk	High Risk	Difference
N	445	319	126	105	21
Overall Survival ITT Probabilities
1	0.91 (0.89–0.94)	0.91 (0.87–0.94)	0.94 (0.88–0.97)	0.94 (0.90, 0.99)	0.90 (0.79, 1.00)	0.04 (−0.10, 0.17)
2	0.83 (0.80–0.86)	0.81 (0.76–0.85)	0.89 (0.82–0.93)	0.91 (0.86, 0.97)	0.76 (0.60, 0.97)	0.15 (−0.04, 0.34)
3	0.74 (0.70–0.79)	0.71 (0.65–0.76)	0.84 (0.75–0.89)	0.88 (0.81, 0.95)	0.63 (0.44, 0.91)	0.24 (0.01, 0.48)
Progression-Free Survival Probabilities
1	0.66 (0.60–0.71)	0.65 (0.59–0.71)	0.68 (0.57–0.76)	0.71 (0.62, 0.82)	0.48 (0.27, 0.84)	0.23 (−0.06, 0.52)
2	0.50 (0.43–0.56)	0.48 (0.41–0.56)	0.54 (0.42–0.65)	0.59 (0.47, 0.73)	0.24 (0.08, 0.75)	0.35 (0.05, 0.65)
3	0.42 (0.35–0.48)	0.41 (0.33–0.49)	0.43 (0.30–0.56)	0.46 (0.33, 0.64)	0.24 (0.08, 0.75)	0.22 (−0.10, 0.53)

ITT, intention-to-treat