Table 1. Characteristics of participants in 2000 according to statin use in the Nurses' Health Study (NHS) and Health Professionals' Follow-up Study (HPFS) *.
| Duration of statin use | ||||
|---|---|---|---|---|
| Nonusers | <2 years | 3-5 years | ≥6 years | |
| Nurses' Health Study | ||||
| No. of participants | 75597 | 7672 | 5048 | 2838 |
| Age (y) | 66.4 | 67.7 | 68.3 | 69.2 |
| Body mass index (kg/m2) | 23.0 | 27.3 | 27.5 | 26.9 |
| Alcohol intake (g/d) | 5.1 | 4.3 | 4.3 | 4.5 |
| Red meat intake (servings/d) | 0.9 | 0.9 | 0.9 | 0.9 |
| Aspirin use, ≥2 tablets/wk (%)† | 14.3 | 25.5 | 25.6 | 29.4 |
| Ever had endoscopy (%) | 52.5 | 59.0 | 60.6 | 63.0 |
| Smoking status (%) | ||||
| Past | 45.2 | 48.4 | 48.7 | 51.7 |
| Current | 9.5 | 8.7 | 9.6 | 9.2 |
| Current multivitamin use (%) | 53.6 | 67.7 | 66.6 | 67.2 |
| Serum cholesterol levels, ≥240 mg/dL (%)‡ | 13.0 | 23.1 | 12.3 | 14.9 |
| Health Professionals' Follow-up Study | ||||
| No. of participants | 33685 | 3315 | 2299 | 1468 |
| Age (y) | 67.9 | 67.4 | 68.0 | 68.7 |
| Body mass index (kg/m2) | 20.2 | 26.0 | 26.4 | 26.3 |
| Alcohol intake (g/d) | 10.8 | 11.0 | 11.1 | 11.2 |
| Red meat intake (servings/d) | 1.2 | 1.0 | 1.0 | 0.8 |
| Aspirin use, ≥2 days/wk (%)† | 28.9 | 62.3 | 66.5 | 67.1 |
| Ever had endoscopy (%) | 68.8 | 78.1 | 78.2 | 79.1 |
| Smoking status (%) | ||||
| Past | 48.6 | 52.8 | 55.2 | 56.5 |
| Current | 5.1 | 3.8 | 3.8 | 3.2 |
| Current multivitamin use (%) | 45.7 | 66.4 | 69.0 | 66.8 |
| Serum cholesterol levels, ≥240 mg/dL (%)‡ | 6.3 | 7.8 | 2.7 | 4.1 |
*
Values are standardized to the age distribution of the study except age. Mean values except those presented as percent
†
Standard (326 mg) tablets
‡
Self-reported total serum cholesterol level