. Author manuscript; available in PMC: 2012 Jun 29.

Published in final edited form as: Sci Transl Med. 2011 Jun 29;3(89):89ra57. doi: 10.1126/scitranslmed.3002156

Table 1. Demographic characteristics and biomarker information for cognitively normal individuals according to APOE genotype.

Values represent means ± SD. When one-way ANOVA was significant, pair-wise comparisons of APOE genotypes were made using Tukey’s post hoc test; only significant differences were indicated

	APOE genotype
	ε2/ε 3	ε3/ε3	ε3/ε4	ε4/ε4
n	32	151	81	19
Female (%)	62.50	64.24	67.90	63.16
Caucasian (%)	87.50	92.05	90.12	84.21
Age at LP, yrs, (SD)	59.28 (7.13)	60.72 (7.17)	60.51 (7.80)	57.58 (8.85)
MMSE	29.28 (0.96)	29.37 (0.94)	29.38 (0.96)	29.32 (1.16)
Education, yrs, (SD)	15.69 (2.76)	15.92 (2.62)	15.83 (2.31)	16.53 (3.42)
Aβ42, pg/mL, (SD)	755.65^‡,^*** (212.85)	695.58^*** (243.87)	619.58^** (193.79)	437.39 (183.53)
Tau, pg/mL, (SD)	253.33 (114.68)	248.72 (126.48)	267.54 (131.89)	244.13 (90.58)
pTau, pg/mL, (SD)	50.72 (17.76)	48.18 (19.71)	55.86 (28.83)	51.45 (13.62)

^‡

P<0.05,

^**

P<0.01,

^***

P<0.001.

‡ denotes significant difference compared to APOE ε3/ε4. ** or *** denotes significant difference compared to APOE ε4/ε4. MMSE, Mini Mental State Examination from 0 to 30.