Table 1.
Demographics and Outcomes of Pregnancies Complicated by Early-Onset, Severe Preeclampsia vs. Controls
| EOSPE (n=50) | Control (n=100) | P value | |
|---|---|---|---|
| Maternal age (years) | 24 (21–30) | 28 (23–32) | 0.001 * |
|
| |||
| BMI (kg/m2) | 34 (27–38) | 28 (24–32) | <0.001* |
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| |||
| African American Race (%) | 48% | 46% | NS † |
|
| |||
| Nulliparous n (%) | 54% | 47% | NS † |
|
| |||
| Gestational age at sample collection (weeks) | 29 (28–31) | 29 (26–31) | NS * |
|
| |||
| Gestational age at delivery (weeks) | 29 (28–32) | 39 (37–40) | <0.001 * |
|
| |||
| Mean Arterial Pressure at Collection of Sample (mmHg) | 125 (116–134) | 78 (71–86) | < 0.001* |
|
| |||
| Birthweight (g) | 1170 (880–1420) | 3260 (2960–3630) | < 0.001* |
|
| |||
| IUGR n (%) | 42% | 10% | <0.001† |
|
| |||
| Vitamin D Status | 0.005† | ||
| Normal (25-OH-D > 32ng/mL) | 24% | 47% | |
| Insufficient (25-OH-D 20–32 ng/mL) | 22% | 26% | |
| Deficient (25-OH-D < 20ng/mL) | 54% | 27% | |
|
| |||
| Plasma 25-OH-Vitamin D (ng/mL) | 18 (13–31) | 32 (20–44) | < 0.001* |
% are provided by columns
BMI = body mass index (prior to pregnancy)
IUGR = intrauterine growth restriction (<10th%ile fetal growth for gestational age)
EOSPE = Early onset, severe preeclampsia
25-OH-D = 25-OH-vitamin D
*
Mann Whitney U test
†
Chi square test