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. Author manuscript; available in PMC: 2011 Oct 13.
Published in final edited form as: Diabetologia. 2006 Jul 26;49(9):2144–2152. doi: 10.1007/s00125-006-0362-9

Table 4.

Whole-body substrate oxidation rates and palmitate kinetics

Basal
Clamp
Control T2DM Control T2DM
Respiratory quotient 0.81±0.01 0.75±0.01a 0.96±0.03b 0.84±0.03a,b
Total fat oxidation 2.7±0.2 3.8±0.2a 0.2±0.7b 2.2±0.6a,b
Total carbohydrate oxidation 6.7±0.6 2.2±1.1a 18.2±1.2b 8.8±2.5a,b
Whole body plasma fat oxidation 1.8±0.3 2.1±0.5 1.2±0.5b 0.7±0.1b
Palmitate rate of appearance 2.8±0.4 3.3±0.5 3.9±0.6 3.7±0.6

Values are mean±SEM; kinetic rates are in μmol min−1 kg−1, palmitate rate of appearance (endogenous + exogenous) is in μmol min−1 kg fat-free mass−1

T2DM Type 2 diabetes mellitus

a

Significantly different from controls (p<0.05)

b

Significantly different from basal values (p<0.05)