TABLE 5.
Young
|
Elderly
|
ANOVA (P value)
|
|||||
---|---|---|---|---|---|---|---|
Basal | Amino acids with glucose | Basal | Amino acids with glucose | Effect of age | Effect of mixture | Interaction | |
Leg glucose kinetics [μmol/(kg·min)] | |||||||
Delivery to the leg | 17.49 ± 2.44 | 26.52 ± 5.55 | 18.29 ± 2.52 | 21.06 ± 4.33 | 0.66 | 0.0343 | 0.21 |
Release from the leg | 16.74 ± 2.17 | 24.65 ± 5.08 | 17.76 ± 2.56 | 20.17 ± 4.27 | 0.73 | 0.0393 | 0.23 |
Net glucose uptake | 0.75 ± 0.31 | 1.88 ± 0.49 | 0.52 ± 0.17 | 0.89 ± 0.21 | 0.13 | 0.0258 | 0.20 |
Whole body glucose kinetics [μmol/(kg·min)] | |||||||
Total Ra | 11.17 ± 0.32 | 18.95 ± 0.85 | 11.06 ± 0.85 | 20.15 ± 1.92 | 0.74 | <0.0001 | 0.48 |
Endogenous Ra | 11.17 ± 0.32 | 1.26 ± 0.88 | 11.06 ± 0.85 | 2.11 ± 1.62 | 0.80 | <0.0001 | 0.54 |
Glucose delivery to the leg, release from the leg, net glucose uptake across the leg, whole body glucose Ra, and endogenous glucose Ra in normal young and elderly individuals in the basal state and during the intake of an amino acid-glucose mixture. Values are the mean ± SE.