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. 2011 Jul 1;5(4):999–1004. doi: 10.1177/193229681100500423

Table 3.

Frequency of Nocturnal Hypoglycemia in the Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Randomized Control Triala

Hypoglycemic threshold

Binary outcomes ≥70 mg/dl ≥60 mg/dl ≥50 mg/dl
% of nights
Single value hypoglycemic 25.4% 14.8% 7.6%

2 consecutive values hypoglycemic 23.3% 13.2% 6.7%

20 consecutive minutesa hypoglycemic 18.4% 9.7% 4.5%

60 consecutive minutes hypoglycemic 9.7% 4.6% 2.0%
a

Continuous glucose monitoring data were evaluated from 10:00 pm to 6:00 am during the first six months of the study in 231 subjects in the CGM treatment group (age 8–72 years, baseline HbA1c 4.7–10.6%). Analysis was restricted to the 25,473 nights with at least 6 h of CGM data, ranging from 3 to 182 per subject.