Table 3.
Frequency of Nocturnal Hypoglycemia in the Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Randomized Control Triala
| Hypoglycemic threshold | |||
|---|---|---|---|
| Binary outcomes | ≥70 mg/dl | ≥60 mg/dl | ≥50 mg/dl |
| % of nights | |||
| Single value hypoglycemic | 25.4% | 14.8% | 7.6% |
| 2 consecutive values hypoglycemic | 23.3% | 13.2% | 6.7% |
| 20 consecutive minutesa hypoglycemic | 18.4% | 9.7% | 4.5% |
| 60 consecutive minutes hypoglycemic | 9.7% | 4.6% | 2.0% |
Continuous glucose monitoring data were evaluated from 10:00 pm to 6:00 am during the first six months of the study in 231 subjects in the CGM treatment group (age 8–72 years, baseline HbA1c 4.7–10.6%). Analysis was restricted to the 25,473 nights with at least 6 h of CGM data, ranging from 3 to 182 per subject.