Table 3.
Parameters of Health Utilities and Discount Rates for the Markov Decision Model
| Parameter | Value | Reference | |
|---|---|---|---|
| Base case analysis | Probabilistic sensitivity analysis distributiona | ||
| Health utilities | Coffey and coworkers58 | ||
| Diabetes without complications | 0.689 | Normal (0.662 to 0.716) | |
| Diabetes with microvascular complications | 0.599 | Uniform (0.519 to 0.678) | |
| Diabetes with macrovascular complications | 0.631 | Uniform (0.617 to 0.645) | |
| Diabetes with microvascular and macrovascular complications | 0.599 | Uniform (0.519 to 0.678) | |
| Discount rates | |||
| Discount rate applied to costs, % | 3.00 | (2.00 to 5.00)b | Assumption |
| Discount rate applied to quality-adjusted life-expectancy, % | 3.00 | (2.00 to 5.00)b | Assumption |
a
Normal (a to b) = normal distribution (95% confidence interval); uniform (a to b) = uniform distribution (minimum to maximum).
b
(a to b) = (minimum to maximum). This parameter was not varied in the probabilistic sensitivity analysis.