Table 1.
Baseline Characteristics
| Characteristic | Placebo (n = 18) | RBX (n = 18) | tpx (n = 18) | p valueb |
|---|---|---|---|---|
| Age (year)a | 57.83 (2.87) | 58.11 (2.02) | 61.06 (1.38) | NS |
| Gender: (female/male) | 3/5 | 3/15 | 5/13 | NS |
| Origin: (cc/aa/other) | 14/4/0 | 14/2/2 | 15/3/0 | NS |
| Height (m)a | 1.77 (0.02) | 1.74 (0.02) | 1.79 (0.02) | NS |
| Weight (kg)a | 103.93 (7.46) | 93.28 (4.37) | 105.19 (5.89) | NS |
| BMI (kg/m2)a | 33.22 (2.21) | 30.71 (1.27) | 32.58 (1.38) | NS |
| Waist circumference (cm)a | 109.62 (5.0) | 108 (3.70) | 113.18 (4.46) | NS |
| HbA1c (%)a | 7.55 (0.25) | 6.93 (0.26) | 7.46 (0.34) | NS |
| SBP (mm Hg)a | 132.17 (3.74) | 133.44 (3.42) | 141.5 (4.50) | NS |
| DBP (mm Hg)a | 73.95 (2.54) | 73.83 (1.78) | 81.83 (2.0) | <.05 |
| Total cholesterol (mg/dl) | 171.0 (9.6) | 174.9 (9.6) | 176.0 (27) | NS |
| LDL (mg/dl) | 99.2 (8.4) | 95.8 (7.1) | 94.0 (7) | NS |
| HDL (mg/dl) | 49.6 (2.9) | 55.1 (4.2) | 46 (3) | NS |
| Triglycerides (mg/dl) | 112.8 (11.7) | 115.7 (18.6) | 176.0 (27) | <.05 |
| NTSS-6 total score (points) | 5.04 (1.12) | 4.82 (0.75) | 7.1 (1.39) | <.05 |
| NSS (points) | 5.8 (0.7) | 5.3 (0.7) | 5.6 (0.65) | NS |
| NIS (points) | 11.3 (1.7) | 7.4 (1.0) | 18.8 (2.15) | <.05 |
| MS (points) | 3.5 (0.4) | 1.7 (0.3) | 3.3 (0.8) | <.05 |
| SS (points) | 7.7 (1.5) | 5.7 (0.8) | 15.5 (1.77) | <.05 |
DBP, diastolic blood pressure; HDL, high-density lipoprotein; LDL, low-density lipoprotein; NS not significant; SBP, systolic blood pressure; cc, Caucasian; aa, African American.
a
Data are presented as mean (± SEM).
b
Between-group difference was measured by Kruskal-Wallis Test for continuous data and by chi-square test for categorical data.