Table 3.

QOL-DN Improvement at Endpoint in the Three Groups^a

QOL domain	Placebo		RBX		TPX
	Difference	p value	Difference	p value	Difference	p value
Total QOL	-5.56 ± 3.49	NS	-9.56 ± -4.13	<.04	-12.22 ± 2.76	<.001
Symptoms	-0.28 ± 0.82	NS	-2.27 ± 0.81	<.004	-4.89 ± 0.88	<.0001
Large fiber	-3.67 ± 2.23	NS	-4.74 ± 2.69	NS	-5.61 ± 1.64	<.05
Small fiber	-1.22 ± 0.69	NS	-0.5 ± 0.36	NS	-1.06 ± 0.56	NS
Activities of daily living	-0.39 ± 0.50	NS	-1.06 ± 0.62	NS	-0.61 ± 0.54	NS
Autonomic	0 ± 0.29	NS	-0.56 ± 0.38	NS	-0.06 ± 0.26	NS

NS, not significant.

^aData presented as mean (± SEM).