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Risk of bias of included trials
| Methodological Characteristics | Percent (number) of Trials |
|---|---|
| Details regarding generation of the randomisation sequence | 88.75% (71/80) |
| Reporting of Allocation Concealment | |
| Maintained | 52.5% (42/80) |
| Unclear | 45.0% (36/80) |
| Not maintained | 2.5% (2/80) |
| Use of any type of blinding | 58.75% (47/80) |
| Presentation of results according to ITT | 71.25% (57/80) |
| Loss to follow-up reported by study arm | 92.50% (74/80) |
Abbreviations: ITT - Intention To Treat.
