Table 3.

Lipid profile: concentrations and ratios, by particle size phenotype and MS status (N = 185)

	Phenotype A (> 260 Å) (N = 127)			Phenotype B (≤ 260 Å) (N = 58)			p-value3
	No MS	MS	p-value1	No MS	MS	p-value2
Plasma cholesterol (mg/dL)	188 ± 35.9	196.1 ± 83.6	0.279	245 ± 56	227 ± 48	0.721	0.001*
Plasma triglycerides (mg/dL)	101 [70-129.3]	129 [91-195]	> 0.001*	282 [265-298]	245 [178-296]	0.529	> 0.001*
LDL cholesterol (mg/dL)	106.4 ± 31.8	112 ± 34	0.413	137 ± 54	124 ± 32	1.000	0.064
HDL cholesterol (mg/dL)	60 [52-69]	53 [41-63]	0.001*	52 [47-56]	42 [38-52]	0.441	0.004*
Apo A-I (mg/dL)	160.6 ± 22.1	159.37 ± 31.7	0.632	168 ± 4.24	158.7 ± 26.5	0.400	0.328
Apo A-II (mg/dL)	31 [28-33]	32 [27-38]	0.212	36.5 [35-38]	34 [30-41]	0.857	0.337
Apo B (mg/dL)	95.4 ± 23.1	105.1 ± 21.4	0.031*	139 ± 24.1	122.5 ± 31.2	0.400	0.001*
Lipoprotein (a) (mg/dL)	18.6 [4.9-43]	14.3 [4.2-33.7]	0.405	1.25 [1.2-1.3]	19.5 [12.9-47.3]	0.012*	0.353
Apo B/Apo A-I ratio	0.60 ± 0.16	0.69 ± 0.19	0.024*	0.83 ± 0.12	0.78 ± 0.18	0.610	0.001*
Plasma cholesterol/HDL-c ratio	3.22 ± 0.84	3.84 ± 1.18	0.001*	4.72 ± 0.50	4.82 ± 1.17	0.889	> 0.001*
Plasma triglycerides/HDL-c ratio	1.65 [1.13-2.45]	2.49 [1.53-3.67]	> 0.001*	5.55 [4.73-6.34]	5.49 [3.99-6.85]	0.963	> 0.001*
Log (TG/HDL-c) ratio	0.20 ± 0.24	0.38 ± 0.29	> 0.001*	0.74 ± 0.08	0.72 ± 0.19	0.963	> 0.001*
LDL particle size (Å)	273.6 [271.1-274.7]	271.2 [267.7-273.7]	> 0.001*	255.25 [255-255.5]	259 [257.6-260]	0.114	> 0.001*

Notes: Data are mean ± SD, and median and interquartile range. * Statistically significant differences.

p-value¹: significance between MS and non-MS in phenotype A patients.

p-value²: significance between MS and non-MS in phenotype B patients.

p-value³: significance between phenotypes.