Table 1. Growth efficiency of the NIBRG-14 and Vero-adapted influenza H5N1 (Vero-15) viruses with different multiplicity of infection (MOI) in T-flasks.
NIBRG-14 (MOI = 10−2) | NIBRG-14 (MOI = 10−3) | Vero-15 (MOI = 10−3) | Vero-15 (MOI = 10−4) | |
Days post-infection | TCID50/ml (log10) | TCID50/ml (log10) | TCID50/ml (log10) | TCID50/ml (log10) |
1 | <2 | <2 | 4.33±0.07 | 3.71±0.10 |
2 | <2 | <2 | 6.80±0.17 | 7.80±0.24 |
3 | 4.16±0.13 | 4.93±0.29 | 7.03±0.23 | 8.30±0.13 |
4 | 4.42±0.07 | 4.78±0.52 | not available | not available |
5 | 4.55±0.13 | 5.53±0.03 | not available | not available |
TCID50 (50% tissue culture infectious dose) was measured in triplicate and shown as geometric mean ± standard error of mean.
Boldfaces indicate peak infectious virus titers.