Table 1. Gene signature predictive of ER status.
Gene Symbol | Correlation Coefficient | Gene Title |
ADCY9 | 0.44 | adenylatecyclase 9 |
AMFR | 0.44 | autocrine motility factor receptor |
ANXA9 | 0.43 | annexin A9 |
0.45 | ||
C6orf97 | 0.45 | chromosome 6 open reading frame 97 |
CA12 | 0.48 | carbonic anhydrase XII |
0.48 | ||
0.47 | ||
0.47 | ||
0.47 | ||
CELSR1 | 0.43 | cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) |
CYP2B6 /// | 0.45 | cytochrome P450, family 2, subfamily B, polypeptides 6, 7 |
CYP2B7P1 | ||
ESR1 | 0.50 | estrogen receptor 1 |
FAM176B | 0.46 | family with sequence similarity 176, member B |
0.43 | ||
GAMT | 0.45 | guanidinoacetate N-methyltransferase |
GATA3 | 0.45 | GATA binding protein 3 |
0.48 | ||
0.47 | ||
GFRA1 | 0.45 | GDNF family receptor alpha 1 |
GREB1 | 0.46 | growth regulation by estrogen in breast cancer 1 |
IL6ST | 0.44 | interleukin 6 signal transducer (gp130, oncostatin M receptor) |
0.44 | ||
KCNK15 | 0.44 | potassium channel, subfamily K, member 15 |
KDM4B | 0.45 | lysine (K)-specific demethylase 4B |
0.46 | ||
0.43 | ||
SCCPDH | 0.43 | saccharopine dehydrogenase (putative) |
SCUBE2 | 0.46 | signal peptide, CUB domain, EGF-like 2 |
LIV1 (SLC39A6) | 0.46 | solute carrier family 39 (zinc transporter), member 6 |
SSH3 | 0.44 | slingshot homolog 3 (Drosophila) |
STC2 | 0.44 | stanniocalcin 2 |
TBC1D9 | 0.43 | TBC1 domain family, member 9 (with GRAM domain) |
TFF1 | 0.44 | trefoil factor 1 |
Unknown | 0.45 | Not annotated |
Each row in the coefficient column represents a probe set. Genes, whose levels of expression were previously reported to correlate with ER status are marked in bold. The rows were sorted alphabetically according to the Gene Symbol. For detailed information on the probe sets see Table S1.