Table 6. Correlation of microarray–based expression profiling data with routinely established PR status.
Total | PR status defined by predictor | Clinical PR status | ||||
Negative | Positive | p-value* | ||||
Training | GSE3494 | 251 | Negative | 45 | 31 | 2.3·10−16 |
Positive | 16 | 159 | ||||
GSE3494** | 251 | Negative | 29 | 17 | <3.3·10−10 | |
Positive | 32 | 173 | ||||
Validation | GSE20271 | 144 | Negative | 63 | 15 | 6.1·10−12 |
Positive | 16 | 50 | ||||
GSE20194 | 278 | Negative | 107 | 22 | <2.2·10−16 | |
Positive | 50 | 99 | ||||
GSE9195 | 79 | Negative | 9 | 24 | 0.1484 | |
Positive | 6 | 40 |
*Fisher's exact test.
**The analysis was performed by using the “best probe set” (“219197_s_at”). The rest of analyses were performed by using the 51-gene PR signature.