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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Neurobiol Aging. 2011 Jul 7;33(4):825.e15–825.e24. doi: 10.1016/j.neurobiolaging.2011.05.014

Figure 2. Fyn levels are reduced in Fyn+/−3xTg+/− mice.

Figure 2

A. Brain lysates from 15, 18, 21, and 24 month old female Fyn+/+3xTg+/− and Fyn+/−3xTg+/− mice were Western blotted for Fyn. Female Fyn+/−3xTg+/− mice showed a 34% decrease at 15 months (p<0.001), a 39% decrease at 18 months (p<0.05), a 60% decrease at 21 months (p<0.01), and a non-significant decrease at 24 months. B. 18, 21, and 24 month old male Fyn+/+3xTg+/− and Fyn+/− 3xTg+/− mice were Western blotted for Fyn. Fyn+/−3xTg+/− mice had a 74% decrease in Fyn levels at 18 months (p<0.001), a 56% decrease at 21 months (p<0.05), and a 55% decrease at 24 months (p<0.01).