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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Int J Obes (Lond). 2011 Jun 28;36(5):718–724. doi: 10.1038/ijo.2011.122

Figure 4. Change in HLA genotype frequency with increasing BMI.

Figure 4

Patients were classified with normal weight (n=1680, white bars), overweight (n=413, grey bars) and obese (n=81, black bars) using ISO-BMI determined after stabilization of diabetes. Proportion of islet autoantibody positive type 1 diabetes patients carrying A1*X-B1*03:02/A1*05:01-B1*02:01 or A1*X-B1*03:02/Z and A1*05:01-B1*02:01/Z genotypes is plotted by BMI class. A test for trend was carried out for each of the genotype groups. X = DQA alleles that have not been genotyped, Z = any DQA1-DQB1 haplotype. Details are shown in Supplementary table 1.