. Author manuscript; available in PMC: 2012 Nov 1.

Published in final edited form as: Int J Obes (Lond). 2011 Jun 28;36(5):718–724. doi: 10.1038/ijo.2011.122

Table 1.

Synergy index between HLA-DQ A1*-B1* genotypes and BMI.

BMI	05:01-02:01/05:01-02:01 neg	05:01-02:01/0501-0201 pos	Synergy index (SIM) (95%CI)	p
Normal weight	1667	70	1.83 (1.21–2.76)	0.006
Overweight or obese	469	36

BMI	0301-0302 neg	0301-0302 pos

Overweight or obese	477	1203	1.37 (1.10-1.70)	0.005
Normal weight	174	320

Synergy index (SIM)= OR_ge/(OR_e × OR_g) when no correlation between exposure and genetic factor was present among controls. The 95% confidence intervals (CI) are shown.