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Dependence of the probability P1(f) (see Eq. 6) to find the allosteric fragment in the bent state a1 (see Fig 2b) as a function of force for P-selectin/PSGL-1 (solid line) and FimH/mannose (dashes). Ligand binding favors the extended state (44), defining the initial value P1(0). The applied force stabilizes the extended state further. The small values of P1(f) justify the approximation leading to Eq. 7.
