Time evolution of scattering profiles. (A) SANS profiles just after dissolving into 81% D2O solutions (blue and red for h-α7 and d-α7 tetradecamers, respectively) and after 12 h (cyan and orange for h-α7 and d-α7 tetradecamers, respectively). (B) Time evolution of SAXS profile after mixing the h-α7 tetradecamers with the d-α7 tetradecamers in 81% D2O solution. (C) Time evolution of SANS profile after mixing the h-α7 tetradecamers with the d-α7 tetradecamers in 81% D2O solution. (D) Time evolution of normalized zero-angle scattering intensity, . Solid circles show the experimental result calculated with the Guinier formula. Cyan line represents the result of the least-square fitting of the biexponential decay function, Eq. 1 (see text), whereas green and blue lines show the best simulated results using the two-subunit-swapping model with (blue) and without (green) the assumption that the swappable subunits are in equilibrium between active and inactive states (Fig. 3B and see text).