Table 4.

Influence of fenugreek and onion combination on biliary lipid profile in mice fed HCD

Animal group	Cholesterol (mM)	Phospholipids (mM)	Bile acids (mM)	Total lipids (g/dl)	CSI	Cholesterol:phospholipid ratio	Cholesterol:bile acid ratio
Basal control	7.88 ± 0.44†	16.9 ± 0.47†	165.6 ± 1.43†	8.69 ± 0.45†	0.91 ± 0.03†	0.47 ± 0.03†	0.045 ± 0.003†
HCD	59.6 ± 0.62	29.8 ± 0.41	162.4 ± 2.18	11.7 ± 0.21	4.14 ± 0.02	2.00 ± 0.02	0.365 ± 0.004
HCD + F	13.2 ± 0.37†	23.0 ± 0.40†	182.3 ± 4.10*	10.7 ± 0.20	1.39 ± 0.37†	0.57 ± 0.02†	0.073 ± 0.003†
HCD + O	23.0 ± 0.48†	19.6 ± 0.14†	206.7 ± 3.50†	11.3 ± 0.25	2.33 ± 0.06†	1.17 ± 0.03†	0.111 ± 0.003†
HCD + F + O	11.5 ± 0.37†	17.4 ± 0.68†	182.8 ± 2.98*	10.3 ± 0.40*	1.37 ± 0.04†	0.67 ± 0.02†	0.063 ± 0.002†

HCD, high-cholesterol diet; F, fenugreek; O, onion; CSI, cholesterol saturation index.

Values are mean ± SEM of six samples, each sample being pooled from three animals.

Statistically significant compared with HCD group

^*P<0.05

^†P<0.01.