Fig. 3.

Behavior/diurnal rhythms are affected in 16p11.2 CNV mice. Comparison of the distance traveled in cohorts of distinct genotypes (detailed in the text) during 60 h of alternating 12-h dark and 12-h light cycles (i.e., spanning three dark periods plus two light periods). (A) The distance traveled over successive dark (black bars) and light (gray bars) periods is shown in bins of 12 h. Five successive dark or light periods are shown. (B) The average distance traveled during light vs. the average distance traveled during dark. (C) The ratio of light-to-dark activity indicates that df/+ mice are unusual in that their activity is not as restricted to the dark periods as the controls are. Average and SEM are presented in all panels.