Table 1.
Colony-forming assays on BM from WT and mutant mouse strains
| Genotype/TAM | ME | Evi1 | HPP-CFC | GEMM | GM | G | M |
|---|---|---|---|---|---|---|---|
| Evi1+/+;Esr-Cre | |||||||
| No | ● | ● | 16.7 ± 1.5 | 18.0 ± 1.0 | 64.7 ± 6.0 | 4.7 ± 1.5 | 7.7 ± 2.1 |
| Yes | ● | ● | 15.7 ± 2.1 | 18.0 ± 2.0 | 63.0 ± 9.0 | 5.3 ± 2.1 | 5.3 ± 3.2 |
| Evi1fl3/+;Esr-Cre | |||||||
| No | ● | ● | 15.7 ± 1.5 | 17.7 ± 1.1 | 54.7 ± 10.7 | 4.7 ± 2.5 | 3.3 ± 0.6 |
| Yes | ◑ | ◑ | 15.0 ± 1.0 | 16.7 ± 0.6 | 51.3 ± 5.9 | 6.7 ± 2.1 | 5.3 ± 2.5 |
| Evi1fl3/fl3;Esr-Cre | |||||||
| No | ● | ● | 16.7 ± 2.1 | 18.7 ± 2.1 | 59.7 ± 7.5 | 7.0 ± 2.6 | 7.0 ± 2.0 |
| Yes | ○ | ○ | 0.0 ± 0.0 | 1.3 ± 0.6 | 4.7 ± 2.5 | 25.3 ± 4.5 | 18.7 ± 4.0 |
A total of 20 000 cells were plated per well in M3434 and colonies were counted at day 12.
TAM indicates tamoxifen.