FIG. 5.

VFA measurements in vivo. a: Linear fit of signals from caudate nucleus (GM, squares, green), splenium (WM, diamonds; red), and lateral ventricle (cerebro-spinal fluid, diamonds, blue). Local flip angle inhomogeneities were corrected before calculating τ. Deviations from the signal equation were observed for nominal flip angles above 18° and excluded. b: Pseudo-color overlay of flip angle corrected T₁ values to enhance the inhomogeneities within WM and deep GM. The distribution across the cortex is degraded by partial volume effects at a resolution of 1.25 mm. c: Whole-brain histogram of T₁ values with color-scale of the overlay.