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. 2010 Aug 17;21(2):275–289. doi: 10.1038/cr.2010.118

Figure 4.

Figure 4

Knockdown of TWIST, MTA2 or RbAp46 specifically inhibits cancer cell migration and invasion. (A-C) Real-time assays of cell migration, invasion and growth for 4T1 cells with non-targeting shRNA (shControl) and targeting shRNAs specific to Twist (shTwist-74), Mta2 (shMta-54 and shMta-56) and RbAp46 (shRp-20 and shRp-21). (D) Western blot analysis for knockdown of TWIST and RbAp46 in MDA-MB-435 cells by shRNAs. (E, F) Real-time assays of cell growth and invasion for MDA-MB-435 cell pools expressing shControl, shTWIST and shRbAp46 (shRp-4 and shRp-7).