Table 2. Model estimated proportional change in NVT and overall number of IPD cases from pre- to 10 years post- PCV7 introduction in England and Wales, stratified by six age groups, based on the point estimate of the adjusted number of IPD cases, and 95% CIs represent the range of results obtained when the adjusted number of IPD cases is varied over its 95% CI.
<5 | 5–14 | 15–44 | 45–64 | 65+ | Total | |
NVT | 136% | 74% | 87% | 87% | 87% | 90% |
95% CI | (84%,161%) | (55%,94%) | (62%,108%) | (62%,108%) | (62%,108%) | (63%,111%) |
Melegaro et al. [5] | 36% | 24% | 27% | 28% | 28% | 28% |
Overall | −42% | −26% | 3% | −1% | −7% | −9% |
95% CI | (−55%,−36%) | (−34%,−17%) | (−11%,15%) | (−14%,10%) | (−20%,3%) | (−22%,2%) |
Melegaro et al. [5] | −63% | −31% | −21% | −28% | −42% | −38% |
The proportional changes in NVT and overall IPD cases from best fitted model in the previous study [5] are included for comparison.