. 2011 Feb 23;7(4):469–484. doi: 10.1007/s11306-011-0289-0

Table 3.

Accurate mass analysis by FT-ICR-MS of glucuronidated and sulfonated hesperetin and naringenin in ‘PRE’, fasting and postprandial urine samples from Study 2

Expected metabolite signal	Theoretical mass	Accurate mass detected by FT-ICR-MS analysis
		PRE^a	Fasting^b	Postprandial samples^c
		PRE^a	Fasting^b	2 h	4 h	6 h	8 h
Hesperetin sulfate [M − H]¹⁻	381.02858	N/D	N/D	N/D	N/D	381.02854 (Δppm 0.10)	381.02848 (Δppm 0.26)
Hesperetin-monoglucuronide [M − H]¹⁻	477.10385	N/D	N/D	N/D	N/D	477.10382 (Δppm 0.07)	477.10384 (Δppm 0.02)
Naringenin monoglucuronide [M − H]¹⁻	447.09329	N/D	N/D	N/D	Trace	447.09336 (Δppm 0.16)	447.09318 (Δppm 0.24)

^a‘PRE’, pool of the pre-test day over-night urine voids

^bFasting, spot urine sample after a 12 h (minimum) fast

^cUrine samples (h postprandial) after the standardized breakfast

N/D not detected, Δppm part-per-million difference compared with the theoretical mass