. Author manuscript; available in PMC: 2012 Nov 1.

Published in final edited form as: J Pediatr. 2011 Jul 23;159(5):720–725. doi: 10.1016/j.jpeds.2011.05.033

Table 2.

Initial empirical antibiotics, total antibiotic exposure, and select adverse outcomes

	Description	Initial Empirical Antibiotic Therapy			p-value
		0 days 60 (16.4%)	1–4 days 175 (48%)	≥5 days 130 (35.6%)
Total days treated with antibiotics during hospital course	Median (range) [IQR]	0 (0–21) [0–0]	3 (1–55) [3–8])	14* (5–84) [8–27]	<.0001
Composite⁺	No. (%)	7 (11.7%)	31 (17.7%)	53 (40.8%)*	<.0001
Late onset sepsis	No. (%)	7 (11.7%)	23 (13.1%)	46 (35.4%)*	<.0001
NEC	No. (%)	0	8 (4.6%)	9 (6.9%)	0.11
Death	No. (%)	0	8 (4.6%)	12 (9.2%)	0.03

⁺

Any outcome of death, sepsis, or NEC after 7 days of life