Table 3.

Multivariable logistic regression for 305 infants who had received any empirical antibiotic therapy

	Odds Ratio	95% Confidence Interval	p-value
Composite outcome: NEC, LOS, Death after DOL 7*
Initial Empirical ABX duration per day	1.24	1.07, 1.44	0.005
Initial Empirical ABX duration ≥5 days	2.66	1.12, 6.30	0.016
Outcome: LOS after DOL 7*
Initial Empirical ABX duration per day	1.27	1.09, 1.49	0.003
Initial Empirical ABX duration ≥5 days	2.45	1.28, 4.67	0.007
Outcome: NEC after DOL 7**
Initial Empirical ABX duration per day	1.08	0.83, 1.40	0.57
Initial Empirical ABX duration ≥5 days	1.28	0.42, 3.93	0.66
Outcome: Death after DOL 7†
Initial Empirical ABX duration per day	1.04	0.82, 1.33	0.74
Initial Empirical ABX duration ≥5 days	1.12	0.40, 3.10	0.83

^*Controlling for birth weight, gestational age, race, prolonged premature rupture of membranes, number of days on high frequency ventilation in first week of life, amount of breast milk received in first 14 days of life

^**Controlling for gestational age, race, number of days on mechanical ventilation in first week of life, amount of breast milk received in first 14 days of life

^†Controlling for birth weight, race, 5-minute apgar <5, amount of breast milk received in first 14 days of life