Table IV.
Hazard ratios (p-values) in Cox PH model using estimated family risk scores and other risk factors as covariates.
| Model with a binary family risk score |
Model with SLFS | Model with Reed et al.’s family risk score |
Model with Williams et al.’s family risk score |
|
|---|---|---|---|---|
| Event of interest: stroke | ||||
| Family risk score | 1.141 (1.2 × 10−1) | 1.198 (1.2 × 10−5) | 0.922 (1.3 × 10−2) | 1.102 (8.3 × 10−4) |
| Cholesterol level | 0.997 (2.2 × 10−2) | 0.997 (2.0 × 10−2) | 0.997 (2.0 × 10−2) | 0.997 (2.1 × 10−2) |
| HDL | 0.988 (2.5 × 10−5) | 0.988 (3.8 × 10−5) | 0.988 (2.8 × 10−5) | 0.988 (2.6 × 10−5) |
| InCrp | 1.066 (7.1 × 10−2) | 1.061 (8.9 × 10−2) | 1.064 (7.7 × 10−2) | 1.065 (7.2 × 10−2) |
| Hypertension | 1.972 (2.1 × 10−12) | 1.920 (1.6 × 10−11) | 1.961 (3.2 × 10−12) | 1.960 (3.3 × 10−12) |
| Diabetes | 1.778 (8.9 × 10−11) | 1.751 (2.9 × 10−10) | 1.769 (1.1 × 10−10) | 1.765 (1.6 × 10−10) |
| Age | 0.917 (<1 × 10−16) | 0.923 (<1 × 10−16) | 0.917 (<1 × 10−16) | 0.917 (<1 × 10−16) |
| Event of interest: myocardial infarction | ||||
| Family risk score | 1.481 (7.8 × 10−10) | 1.269 (5.3 × 10−15) | 0.835 (<1 × 10−16) | 1.188 (3.3 × 10−14) |
| DBP | 0.992 (1.9 × 10−2) | 0.992 (2.3 × 10−2) | 0.992 (2.0 × 10−2) | 0.992 (1.6 × 10−2) |
| Cholesterol level | 0.991 (<1 × 10−16) | 0.991 (<1 × 10−16) | 0.991 (<1 × 10−16) | 0.991 (<1 × 10−16) |
| HDL | 0.978 (<1 × 10−16) | 0.978 (<1 × 10−16) | 0.978 (<1 × 10−16) | 0.978 (<1 × 10−16) |
| InCrp | 1.068 (2.6 × 10−2) | 1.061 (3.1 × 10−2) | 1.062 (2.8 × 10−2) | 1.064 (2.3 × 10−2) |
| Hypertension | 1.409 (2.3 × 10−6) | 1.366 (1.0 × 10−5) | 1.404 (3.1 × 10−6) | 1.392 (5.5 × 10−6) |
| Diabetes | 1.532 (1.8 × 10−9) | 1.507 (7.5 × 10−9) | 1.529 (2.3 × 10−9) | 1.518 (3.9 × 10−9) |
| Age | 0.975 (1.3 × 10−7) | 0.982 (2.7 × 10−4) | 0.976 (3.4 × 10−7) | 0.974 (5.6 × 10−8) |