Table 1.
Patient Characteristics at Baselinea
| Characteristic | DP treatment (n = 248) | CQ treatment (n = 244) |
| Asexual parasitemia, geometric mean (95% CI), μL−1 | 3776 (3111–4582) | 4406 (3637–5339) |
| Gametocytemia, geometric mean (95% CI), μL−1 | 214 (178–257) | 280 (236–333) |
| Gametocytemia present | 85 (210) | 84 (205) |
| Schizonts present at enrollment | 32 (79) | 30 (74) |
| Male sex | 70 (173) | 64 (155) |
| G6PD deficiency | 6.1 (15/247) | 5.3 (13) |
| Weight, median (range), kg | 45 (7–74) | 45 (9–61) |
| Age, median (range), years | 18 (1–57) | 18 (1–63) |
| Age, years | ||
| <5 | 14 (34) | 12 (30) |
| 5–14 | 27 (67) | 29 (70) |
| >14 | 59 (147) | 59 (144) |
| Fever >38.0°C | 42 (94/225) | 42 (97/229) |
| Duration of febrile illness, median (range), days | 2 (0–8) | 2 (0–5) |
| Hematocrit, mean (SD), % | 37.2 (5.0) | 37.6 (5.2) |
| Anemia (hematocrit <30%) | 4.5 (11/247) | 5.8 (14/242) |
| Splenomegaly | 14 (34/243) | 12 (29/237) |
| Hepatomegaly | 23 (57/247) | 26 (63) |
Abbreviations: CI, confidence interval; CQ, chloroquine; DP, dihydroartemisinin-piperaquine; SD, standard deviation.
a
Unless otherwise indicated, data represent % (No.) of patients, with denominators where these were smaller than the full sample.