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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: NMR Biomed. 2011 Jul 12;25(2):271–278. doi: 10.1002/nbm.1745

Figure 1.

Figure 1

In vivo non-localized 13C spectra from a subcutaneously implanted R3230Ac tumor before (A) and after 30 hours (B) of [2-13C]-glycine infusion at a rate of 0.5 mmol/kg/h. (C) A spectrum from an analogous study employing [2-13C]-glycine infusion at a higher rate of 1 mmol/kg/h. [2-13C]-glycine ([2-13C]-gly) appears at 42.4 ppm, and incorporation into the glycinyl-residue of glutathione ((2-13C-gly)-GSH) is visible at 44.2 ppm. Also detected are labels in two carbons of serine, [2-13C]-ser and [3-13C]-ser and creatine, ([2-13C]-creatine).