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. 2011 Oct;166(1):16–25. doi: 10.1111/j.1365-2249.2011.04443.x

Table 2.

Overview of results from studies using subcutaneous immunoglobulin (SCIG) and intravenous immunoglobulin (IVIG) for replacement therapy and immunomodulation in multi-focal motor neuropathy (MMN)

Number of patients Study design SCIG switch Primary end-point Result Number continuing with SCIG* Study
10 50% dose (n = 5) Muscle strength 50% SCIG < IVIG 0/4 Eftimov et al., 2009 [29]
100% dose (n = 5) 100% SCIG = IVIG 4/5
9 100% dose Muscle strength SCIG = IVIG 5/9 Harbo et al., 2009 [28]
SCIG–IVIG cross-over
8 100% dose Muscle strength SCIG = IVIG 7/7 Misbah et al., [30]
*

Patients who completed the study and for whom data were analysed.