Table 5. Incidence of grade 3 or 4 neutropenia, febrile neutropenia and thrombocytopenia.
Grade 3 or 4 event, n (%) |
Dose reduction |
||
---|---|---|---|
⩾12 Months (n=25) | <12 Months (n=39) | No dose reduction (n=52) | |
Neutropeniaa | 16 (64) | 26 (67) | 20 (39) |
G-CSF | 7 (44) | 12 (46) | 10 (50) |
No G-CSF | 9 (56) | 14 (54) | 10 (50) |
Febrile neutropeniab | 1 (4) | 3 (8) | 1 (2) |
Thrombocytopenia | 2 (8) | 12 (31) | 3 (6) |
No events | 9 (36) | 9 (23) | 30 (58) |
Abbreviation: G-CSF, granulocyte colony-stimulating factor.
Neutropenia included the terms ‘neutropenia', ‘febrile neutropenia' and ‘neutrophil count decreased'.
Febrile neutropenia included the terms ‘febrile neutropenia' and ‘neutropenic sepsis'.