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. 2011 Jul 12;25(10):1620–1626. doi: 10.1038/leu.2011.126

Table 5. Incidence of grade 3 or 4 neutropenia, febrile neutropenia and thrombocytopenia.

Grade 3 or 4 event, n (%) Dose reduction
  ⩾12 Months (n=25) <12 Months (n=39) No dose reduction (n=52)
Neutropeniaa 16 (64) 26 (67) 20 (39)
 G-CSF 7 (44) 12 (46) 10 (50)
 No G-CSF 9 (56) 14 (54) 10 (50)
Febrile neutropeniab 1 (4) 3 (8) 1 (2)
Thrombocytopenia 2 (8) 12 (31) 3 (6)
No events 9 (36) 9 (23) 30 (58)

Abbreviation: G-CSF, granulocyte colony-stimulating factor.

a

Neutropenia included the terms ‘neutropenia', ‘febrile neutropenia' and ‘neutrophil count decreased'.

b

Febrile neutropenia included the terms ‘febrile neutropenia' and ‘neutropenic sepsis'.