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. 2011 Aug 3;36(12):2477–2487. doi: 10.1038/npp.2011.136

Figure 4.

Figure 4

Mean (±SEM) acetylcholine (ACh) efflux in the medial pre-frontal cortex (mPFC) of postnatal day (PD)7 VHTTX rats (n=6) and sham controls (n=5) receiving systemic injections of amphetamine (AMPH; 2 mg/kg, intraperitoneally) or saline as adults. Following baseline (collection nos. 1–4), AMPH or saline was injected. Administration of AMPH resulted in significant and equivalent increases in cortical ACh efflux in both sham and nVHTTX animals that began in collection no. 5 and persisted for the duration of the dialysis session (collection no. 11).