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. 2011 Jul 27;36(12):2513–2528. doi: 10.1038/npp.2011.140

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Copyright © 2011 American College of Neuropsychopharmacology

This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Intrinsic membrane properties of MSNs recorded from control and EtOH monkeys are slightly different. (a and b) Responses to hyperpolarizing and depolarizing current injections in cells recorded from MSNs from slices obtained from control (panel a) and EtOH (panel b) monkeys. (c and d) Capacitance (panel c) was unchanged, whereas input resistance was slightly lower in EtOH than in controls (panel d). (e)The resting membrane potential and the action potential threshold were more depolarized in EtOH compared with controls. (f) The relationship between depolarizing current injection and the frequency of action potentials elicited. ^*Statistically significant differences from control at P<0.05.