Table 3.
Multivariate Logistic Regression Analysis of the Interaction Between Individual Protective Factors in 89 Spontaneous Resolvers and 234 Chronically Infected Individuals
| SR, n (%) | Chronic, n (%) | P value | OR | 95% CI | |
|---|---|---|---|---|---|
| 860-CC | 62 (69.7) | 102 (43.6) | <.001 | 2.99 | 1.64−5.43 |
| 2DL3:C1 homozygous | 26 (29.2) | 31 (13.2) | .04 | 2.94 | 1.06−8.20 |
| 860CC+2DL3:C1 homozygous | 19 (21.3) | 17 (7.3) | >.1 | 0.75 | 0.21−2.67 |
NOTE. The 3 variables included in this analysis were IL28B.rs12979860CC (860-CC), KIR2DL3:HLA-C group 1 homozygosity (2DL3-C1), and IL28B.rs12979860CC in combination with KIR2DL3:HLA-C group 1 homozygosity (860-CC+2DL3-C1).
95% CI, 95% confidence interval; Chronic, chronically infected HCV patients; OR, odds ratio.