Table 2.
Types of Androgen deprivation therapy
| Drug Class | Frequency (%) | Duration in months* | T score† | Osteopenia (%) | Osteoporosis (%) | |
|---|---|---|---|---|---|---|
| Median | 25th and 75th percentile | |||||
| Multiple drugs | 34.6 | 17.4 | 9.3, 56.2 | -1.8± 1.4 | 33 | 46 |
| LHRH analogues | 28.6 | 17.9 | 9.3, 29.6 | -1.5± 1.5 | 42 | 24 |
| Oestrogens | 9.8 | 60.5 | 22.2,67.8 | -0.7± 1.6 | 38 | 7 |
| Anti-androgens | 11.3 | 3.3 | 0.7, 15.9 | -0.9± 2.2 | 33 | 27 |
| Orchiectomy | 15.7 | 43.4 | 15.7, 79.6 | -1.8± 1.4 | 43 | 38 |
Values are percents.
† Values are means ± s.d.
*p <0.001: Overall comparisons of medians/ranks across drug classes.
Abbreviations- LHRH- Luteinizing hormone releasing hormone.
Multiple drugs- Exposure to 2 or more different types of androgens.