Table 4.
Pathways over-represented in genes with SNPs modifying splicing
| Pathway | Count | % | P-Value |
|---|---|---|---|
| Focal adhesion | 30 | 3.5 | 5.9E-6 |
| ECM-receptor interaction | 17 | 2.0 | 5.7E-5 |
| Metabolism of xenobiotics by cytochrome P450 | 12 | 1.4 | 2.3E-3 |
| ABC transporters - General | 9 | 1.1 | 4.9E-3 |
| Bladder cancer | 7 | 0.8 | 3.1E-2 |
| Regulation of actin cytoskeleton | 21 | 2.5 | 3.3E-2 |
| Adherens junction | 10 | 1.2 | 3.3E-2 |
| Phenylpropanoid biosynthesis | 3 | 0.4 | 6.3E-2 |
| Colorectal cancer | 10 | 1.2 | 7.0E-2 |
| Small cell lung cancer | 10 | 1.2 | 7.8E-2 |
| Cyanoamino acid metabolism | 3 | 0.4 | 8.0E-2 |
| Non-small cell lung cancer | 7 | 0.8 | 9.2E-2 |
| Pathogenic Escherichia coli infection - EPEC | 7 | 0.8 | 9.8E-2 |
The overexpressed pathways are shown together with the number of genes involved in the pathway (Count), the percentage of genes involved in the pathway compared to all input genes (%), and the p value from the Fisher test calculated by the DAVID tool.