Figure 12.

E. coli, core genome vs pangenome Core vs. pangenome plots of 41 E. coli strains calculated using original annotations and multigene annotations, predicted by CAMBer. Strains are sorted (from left to right) in descending order of their genome sizes. Violet and green (coregenome-annot and pangenome-annot) lines connect cumulative numbers of core and pangenome sizes using annotated genes, while red and blue (coregenome-multi and pangenome-multi) lines connect cumulative numbers of core and pangenome sizes using multigenes after the closure procedure. The proportion of core genome to pangenome size has risen from 18% to 25% after the closure.