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Effect of mechanical stretch and IL-10 on MMP-9 release in epithelial cells and fibroblasts. Release of MMP-9 into the supernatant of E18–19 epithelial cells (a) and fibroblasts (b) exposed to 20% cyclic stretch for 48 h in the presence or absence of rIL-10 (300 ng/ml). Unstretched cells served as controls. Supernatants were collected and processed by ELISA, as described in “Material and Methods”. Values are in ng/ml and are mean ± SEM from three to five different experiments. *P < 0.05
