Figure 6. Epithelial CXCL10 protein secreted into the basolateral compartment increases with increasing T cells numbers and increasing IFNγ and TNF amounts, reaching a plateau at high concentrations.

A constant number of HNEC (0.5×10⁶ cells) was co-cultured with increasing numbers of activated T cells (0.1, 0.5, 2.5, 5×10⁶ cells). CXCL10 protein amounts secreted by HNEC into the basolateral media are expressed as a function of the numbers of T cells in co-cultures (A) and the amounts of IFNγ (B) and TNF (C) secreted by increasing numbers of T cells.